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In addition, the radiation effect is potentiated by HBOT, increasing the intracellular production of NOS and consequent increase in tumor cell damage ( Figure 1 )

Statements Author contributions JD: Validation, Writingoriginal draft, Conceptualization, Writingreview and editing

Conclusions In this review, we have focused on three aspects: the reactivity of FRs, their cellular effects, and the potential use of antioxidants as scavengers of FRs and their role in cellular metabolism

doi: 10.1038/srep13953 51 CortsJHidalgoJAguileraSCastroIBritoMUrraHet al

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