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Various new screening methods have been used to identify inhibitors and related compounds that target DUBs

Third, we found that GSH depletion induced SIPS

Although the present study does not elucidate why SerpinB2 is required for VAT resident macrophage survival in obesity but not in the steady state, inflammation after initiation of an HFD may be a determinant of macrophage apoptosis in the absence of SerpinB2