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MEL has also been shown to alleviate MS stress-induced insulin resistance and that it sensitizes cells to apoptosis by inhibiting COX expression, increasing the Bax/Bcl-2 ratio and chemotherapy regimen (CHOP) (231)

this review describes a DAG-sensitive PKC and PKD isoforms and their role in the regulation of metabolism

2.2 Spermatogenesis Spermatogenesis is a highly ordered program of germ-cell differentiation comprising three phases: (i) mitotic proliferation and fate specification of spermatogonial stem cells (SSCs), (ii) meiosis of primary and secondary spermatocytes, and (iii) spermiogenesis, the post-meiotic remodeling of spermatids into spermatozoa

doi: 10.1111/pce.13907