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Cancer cells often experience resistance to chemotherapeutical agents and experiments on cellular models proved that antioxidants can increase the sensibility and efficacy of chemotherapy (Guestini et al

This symptom is heavily driven by neuroinflammation and a breakdown of the blood-brain barrier

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In fact, GGT-positive foci were found in animals exposed to prooxidant carcinogens, suggesting the hypothesis of GGT as an early marker of neoplastic transformation [40, 41]