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Description

Encourages metabolic function

10.1001/archopht.118.5.666 Arch

Hayne D, Vaizey CJ, Boulos PB

Mechanistically, the CD73/A2AR signaling cascade coordinates the de novo synthesis and consumption of GSH with GSSG accumulation and concomitant mitochondrial lipid peroxidation, which links potentially to PKA/E2F1dependent fine-tuning of the ratio of GSR to GPX4