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Mechanism of Action Inhibits prostaglandin synthesis in the CNS Acts on the hypothalamus to reduce fever Minimal peripheral anti-inflammatory effect Indications (Uses) Fever (adults and children) Mild to moderate pain: Headache Toothache Muscle pain Postoperative pain Osteoarthritis Dysmenorrhea Often combined with other drugs (e.g., codeine, caffeine)

The ability of the immune system to ignore food particles (oral tolerance) is an active process in which the immune system remains unresponsive to an antigen

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The first observation of pyroptosis was during an experiment in which macrophages were infected with Salmonella enterica serovar Typhimurium (S

Major classical NMD targets include mRNAs harboring PTCs within internal exons