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Though it may be easy to consume enough B12 in your diet, many people have trouble accessing the vitamin from food

IGF-1 replacement therapy induced a restoration of the altered GH/IGF-1 axis by reducing circulating GH levels and recovering the somatostatinergic tone [292]

The investigators interpreted the findings as direct pharmacological validation of the NNMT-knockdown phenotype reported earlier in the Kraus 2014 genetic-validation study