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Whether these options can simultaneously be viable commercially will depend on cost, practicality, and efficacy, which are yet to be determined

However, it is important to note that no animal model can fully mimic the complex and multifactorial nature of FM in humans 31

Folic Acid Supplementation Folic acid or folate is a soluble B vitamin that is important for epigenetic modulation [32], immune regulation [33], and cell repair in the CNS [34]

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In the past, glucocorticoids in allergic features and ursodeoxycholic acid in cholestatic cases had been used, but there is no good evidence to support their effectiveness