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However, randomized, double-blind, placebo-controlled studies demonstrated a significant dose-dependent increase in body stores of glutathione with 250 or 1,000 mg/day of preformed glutathione and a decrease in oxidative stress biomarkers

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Nature 591 , 645651 (2021)

In a simple manner, Kyn can be metabolized either to kynurenic acid (KYNA), with neuroprotective properties, or to the neurotoxic components quinolinic acid (QA) and 3-hydroxykynurenine (3-HK) [208]

The patient gave a history of self-ingestion of paraquat poison in small quantities, followed by nausea and vomiting and admission to the medical ward