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In vitro studies further demonstrate that the cross-linked vesicles act as a reservoir, sustaining cumulative drug release over 48 h under intracellular-mimicking conditions

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Elderly patients with cardiac conditions or those taking loop or thiazide diuretics may be particularly vulnerable

Use of trazodone as an adjunctive agent in the treatment of canine anxiety disorders: 56 cases (1995-2007)

In adult patients with T2DM, intramuscular injections (eight to 10 loading injections of 1,000 g each over one to two weeks, followed by monthly 1,000-g injections) or oral vitamin B12 1,000 to 2,000 g daily are sufficient to correct vitamin B12 deficiency.9 Patients should be monitored for response to therapy