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Nat Rev Clin Oncol 9(5):297303 Mazzone M et al (2009) Heterozygous deficiency of PHD2 restores tumor oxygenation and inhibits metastasis via endothelial normalization

It is the largest and most structurally complex vitamin, and the only one to contain a metal ion, cobalt

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If any health condition bothers you, consult a physician