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Alanine (Ala), the smallest chiral amino acid, serves as an ideal probe for alanine-scanning mutagenesis (Figure S2)

335 As documented in this section and Table 3, antineoplastic agents/methods with ROS-inducing potential and their ROS-mediated antitumor mechanismscompiled from sources including the FDA database (www.fda.gov), ClinicalTrials.gov, and DrugBank ( diverse mechanisms of action ranging from metabolic interference to direct oxidative damage

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Riscal R, Gardner SM, Coffey NJ, et al

Oncogenic signaling The most systematically addressed regulatory influence on CME so far is oncogenic signaling by which tumor cells adapt CME for their purposes [27]