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The use of hormone replacement therapy (HRT) can prevent many of these changes, increasing extracellular matrix components, skin hydration and elasticity and reducing wrinkles [8082]

Drug concentration was determined using LCMS/MS analysis, with serum concentration 1000 mIU/mL (ULQ) were assessed in logistic regression models

Conclusion: The outcomes and adverse events were generally similar between LEN and Atez/Bev in the elderly

Safety of melatonin in pregnant and nursing women is not thoroughly documented, and usage should be approached with caution, as noted in studies by Andersen et al