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Elevated NAD+ activates sirtuins (SIRT1, SIRT3)

Reduced Glutathione provides glutathione in its biologically active reduced form for optimum absorption

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shortens action potential duration Class IC : Exerts strong sodium channel blockade with minimal impact on action potential duration While all Class I agents share a common mechanismsodium channel inhibitiontheir differing electrophysiologic profiles result in varied clinical applications and risks (11)

Lipid Peroxidation Since hypoxia exposure led to increased oxidative stress, we determined the levels of lipid peroxidation