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Given the interaction between the GSH/GPX4 axis and A2AR signaling in CD8 + T cells, we next investigated the molecular mechanism underlying regulation of GPX4 by A2AR signaling in activated CD8 + T cells

View the step-by-step RNA extraction and RT-qPCR protocol used to generate this data Phenotypic characterisation of a human iPSC-derived tri-culture using ioGlutamatergic Neurons, ioAstrocytes, and ioMicroglia Using our fully optimised protocol, ioGlutamatergic Neurons (MAP2, red), ioMicroglia (IBA1, yellow) and ioAstrocytes (vimentin, cyan) were co-cultured to create a highly defined CNS model

Kohno H, Tanaka T, Kawabata K, Hirose Y, Sugie S, Tsuda H, Mori H

Specifically, AHK-Cu might increase the expression of Bcl-2, an anti-apoptotic molecule, while reducing the levels of Bax, a pro-apoptotic counterpart

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