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Thus, MetAP2 inhibition has potential as a minimally toxic, non-competing therapy that could complement current targeted therapies such as those inhibiting the VEGFR pathway or cytotoxic drugs [1,2,3,4]

As a formerly FDA-approved peptide with established dosing protocols, well-characterized safety data, and demonstrated efficacy in pediatric GH deficiency and aging populations, it represents the more thoroughly validated option

Still, for office workers and gym-goers cycling through back-to-back infections every monsoon and winter season, it's a reasonable piece of the puzzle

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Int J Mol Sci 23(16):9339 Trist BG et al (2021) Superoxide dismutase 1 in health and disease: how a frontline antioxidant becomes neurotoxic