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The recent advancements of ferroptosis of gynecological cancer

Schlicker, C

Nat Commun 2023;14(1):6638

DHODH is an enzyme involved in pyrimidine synthesis that can reduce CoQ to CoQH2 in the inner mitochondrial membrane (Lei et al., 2022)

This provides a rationale for the early use of high dose GSH treatment to quantitatively enhance host immune responses and numerically overwhelm the blocking pox virus protein(s)