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Advise patients that there will be a pregnancy exposure registry that monitors pregnancy outcomes in women exposed to ZEPBOUND during pregnancy [see Use in Specific Populations (8.1)]

[DOI] [PMC free article] [PubMed] [Google Scholar] 74.Hansen W., Hutzler M., Abel S., Alter C., Stockmann C., Kliche S., Albert J., Sparwasser T., Sakaguchi S., Westendorf A.M., et al

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(2017) demonstrated that the application of a mitochondrial fusion promoter (M1) and an inhibitor of mitochondrial fission (Mdivi-1) resulted in a significant increase in the copy number of mtDNA