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We further characterized the organoids by imaging against a panel of hepatic markers for hepatocytes (HNF4 and ASGR1), macrophages (Kupffer cells) (CD68), cholangiocytes (CK7), hepatic stellate cells (SMA) and vasculature (CD31), where all markers were represented (Supplementary Fig

8,9,10,11,12 PSCs also interact with endothelial cells via VEGF- and HGF-mediated signalling pathways

Oligodendrocytes upregulate blood-brain barrier function through mechanisms other than the PDGF-BB/ PDGFR pathway in the barrier-tightening effect of oligodendrocyte progenitor cells