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The prescribing information for isotretinoin states that "blood lipid determinations should be performed before isotretinoin is given and then at intervals until the lipid response to isotretinoin is established" [1]

The selected temperature was well above the thermoneutral zone to ensure exposure to heat stress, while the 4-hour duration was sub-lethal, sufficient to induce chronic stress without causing acute mortality

Non-heme iron is found in plant foods like grains, beans, and vegetables, while heme iron is in animal products like meat and fish