glutathione peroxidase thioredoxin reductases and Systems Physiological functions of thioredoxin and

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The liver is particularly vulnerable to alcohol-induced damage due to its central role in metabolizing alcohol and filtering toxins from the bloodstream [6, 7]

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Deux formes de mlanine coexistent : l'eumlanine, pigment brun-noir responsable des teints foncs, et la phomlanine, pigment jaune-rouge associ aux teints plus clairs

Moreover, ALA exerts antioxidant effects via a dual mechanism: (i) rapid redox-cycling between its disulfide (ALA) and dihydrolipoate (DHLA) forms, which directly quenches ROS without transcriptional activation, and (ii) secondary upregulation of the Nrf2 pathway and suppression of NF-B nuclear translocation (Ghibu et al., 2009)