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To be clear, any claims regarding therapeutic benefits are based on preliminary findings in non-human models

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72 Data-independent, ion mobility-enabled, high-definition mass spectra and tandem mass spectra were acquired using the positive ion mode

Even if it is still unclear whether OS is a primary or a secondary cause of neurodegeneration in ALS, overwhelming evidence indicates the pathological role of OS, and alterations in KEAP1 and NRF2 expression and in KEAP1-NRF2 activity may explain the progressive MN degeneration and death associated with ALS [170]