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As a component of the Krebs cycle (Citric Acid Cycle), fumaric acid plays a key role in generating energy

This can also indirectly prevent downstream inflammation, thus altering disease progression

The way2drug (PASS online) tool was utilized to predict the computational ( in-silico ) probable toxicity for the ECGC compound

Western blot assay BEnd3, bEnd3-GGT/KD, HBMEC, RBMEC, G422, and RAW 264.7 cells were seeded in a 6-well plate and cultured overnight

The metallic activators group is represented by metallic cations monovalent or bivalent like K + , Mn ++ , Mg 2+ , Ca 2+ or Zn 2+ , which are indispensable to the activities of a large groups of enzymes