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Heavy metal stress (Cd and/or Pb) in plants results in the overproduction of ROS, which is regulated by antioxidant defense systems that include non-enzymatic antioxidants including GSH, enzymatic antioxidants (SOD, APX, CAT, POX, and GR), carotenoids, -TOC, and proline (Semida et al., 2018)

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PMID: 40507921 Int J Mol Sci2024 Dec 21;25(24):13673

Trofinetide appears to promote synaptic maturation and restore dendritic morphology, neuronal signaling, and synaptic protein synthesis to normal (152)