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Cumulative effect of simvastatin, L-arginine, and tetrahydrobiopterin on cerebral blood flow and cognitive function in Alzheimers disease

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Normally, cells prefer to degrade glucose through aerobic glycolysis, which produces pyruvate that enters the mitochondria in the Tricarboxylic Acid Cycle (TCA) cycle, and subsequently in the electron chain transport, which led to the production of 32 ATP molecules from a single glucose fraction [8]

Sarcopenia aetiology is multi-factorial, driven by progressive anabolic resistance to nutrition and physical activity [36, 37], and age-related structural (vertebral compression and unfavourable fat deposition [38]), metabolic (reduced basal metabolic rate [39]) and hormonal (lower circulating anabolic hormones (testosterone, growth hormone and insulin-like growth factor-1)) changes

doi:10.1179/1973947815Y.0000000048