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In essence- they cant use or absorb this form of B12it just makes for expensive poo

JR: Methodology (supporting), Supervision (equal), Writing-reviewing and editing (equal), Resources (equal)

51,52 Mtb infection activates both of these NLRs in an ESX-1-dependent manner to trigger various host downstream innate immune responses, such as NLRP3 inflammasome formation, autophagy initiation and NF-B and IRF3 pathway activation, which have been extensively reviewed elsewhere