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(2004) Proceedings of the National Academy of Sciences (PNAS) , 101(39): 1490714912 Foundational study identifying the EPO/-common receptor heteromer (IRR) as the mediator of EPOs tissue-protective effects, distinct from the EPOR homodimer responsible for erythropoiesis

In physical dependence assay (isoniazid challenge assessed at 6, 14, 42 and 72 h after conditioning medication), when compared to diazepam non-conditioned healthy mice, in diazepam conditioned mice residual anticonvulsive activity was not present already at the earliest post-conditioning interval (i.e., not different latency to isoniazid-convulsions), whereas shorter preconvulsive latencies (as physical dependence/withdrawal hallmark) were noted in diazepam conditioned mice following isoniazid challenge at 42 h and at 72 h after end of conditioning treatment

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3a), which also exhibited higher levels of PrP protein compared to parental WT HepG2 cells (Fig