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Interestingly, TDP-43 proteopathy is exacerbated in the presence of optineurin (OPTN) mutations, the genetic factor responsible for such accumulation (Thakur et al

Warfarin was given intragastrically (1.5 mg/kg) once daily for 3 consecutive days, with the last challenge was at 3 hours before the bleeding procedure

Comprehensive cancer pre-screening represents a crucial component of patient evaluation due to the potential for these peptides to stimulate angiogenesis, which could theoretically promote malignant growth and metastasis

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