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As reviewed recently, statins are found to modulate the nuclear factor erythroid two related factor 2/heme oxygenase-1 signaling pathway in different diseases (Mansouri et al., 2022)

The mechanism involved in this metabolic supply of cysteine includes export of GSH from astrocytes, extracellular processing of the exported GSH by ectoenzymes, and uptake into neurons of the amino acid precursors for GSH synthesis

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JungSLeeDMoonJHongSShinJHwangIet alL-Ascorbic acid can abrogate SVCT-2-dependent cetuximab resistance mediated by mutant KRAS in human colon cancer cells