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2.1 De novo pathway In mammalian cells, tryptophan 2,3-dioxygenase or indoleamine 2,3-dioxygenas catalyze kynurenine pathway to obtain NAD + from dietary tryptophan (Figure 1)

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Conclusions The hepatic symptoms of Wilsons disease are diverse, ranging from asymptomatic or accidental liver abnormalities to cirrhosis and acute liver failure, and they can onset at any age