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Elevated levels of TMAO in the bloodstream are linked to an increased risk of hypertension and other cardiometabolic disorders [67]

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Traditional ED treatments such as sildenafil (Viagra), vardenafil (Levitra, Staxyn), and tadalafil (Cialis) are often also used to treat pulmonary hypertension

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(8) One study found that the ED drug alprostadil in combination with ALA (60 mg alprostadil and 600 mg ALA, given intravenously once per day for two weeks) improved both endothelial and erectile function in diabetes patients with ED