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Concurrently, oxidative stress can reduce EAAT2 activity or expression through oxidative modification of transporter proteins or damage to its encoding gene

Trends in Cell Biology , 28 (1), 3445

The compound was also investigated as PL14736 in early-phase IBD clinical work, as described in a 2008 paper by Klicek and colleagues in Journal of Pharmacological Sciences , though that clinical program was never completed or approved

Laemmli [29] method was used while performing SDS-PAGE, as explained by Tsugama [30]

Mechanisms for preventing hepatotoxicity induced by oxidative stress involve blocking the chain reaction of oxidation, improving phase II antioxidant enzyme activity, and increasing levels of antioxidant substances