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199 Iron status was also improved in stage 3a CKD patients treated for nearly four months with mixtures of Bifidobacterium and Lactobacillus species in a randomized placebo-controlled trial with 28 participants

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Vitamin B12 and folic acid supplementation and plasma total homocysteine concentrations in pregnant Indian women with low B12 and high folate status

Elderly patients, who may have lower metabolic efficiency, could experience slower collagen deposition partly due to less robust proline biosynthesis, making nutritional support important (e.g., supplementation with proline-rich gelatin or vitamin C to aid proline hydroxylation) [41]

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