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doi: 10.1093/jac/33.suppl_A.23 143 MinardiD.d'AnzeoG.CantoroD.ContiA.MuzzonigroG

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Beyond buying time: the role of plasticity in phenotypic adaptation to rapid environmental change

The age-related increase in arborization of the apical tree of xCT +/+ mice -once again an event which was not seen in xCT / mice- was restricted to the mid-apical dendrites ( stratum radiatum ) where the CA1 neurons receive extensive glutamatergic input of the Shaffer collaterals, possibly representing a compensatory reaction induced by excitotoxic damage in the aged hippocampus, as described in ischemia [84]