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Making migraine easier to stomach: the role of the gut-brain-immune axis in headache disorders

Recent studies have showed that oral ingestion of L-carnitine in both animals and humans results in generation of trimethylamine by intestinal microbiota, which is absorbed and then metabolized to trimethylamine-N-oxide (TMAO) by liver flavin monoxygenases (FMOs) (especially FMO3 and FMO1) 35,45

391-396.Google Scholar CHIODI, P., CIANI, B., KENTROTI, S., MACCARI, F., VERNADAKIS, A., ANGELUCCI, L

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