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Other key signaling pathways that are utilized are the mitogen-activated protein kinase (MAPK) and phosphatidylinositol 3-kinase/AKT/mammalian target of rapamycin (PI3K/AKT/mTOR) pathways, as well as SH2B1, a scaffold protein that interacts with JAK2 and mediates GH-induced changes in the cytoskeleton

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Several reporters left the public with the impression that high carnitine intake was even more responsible for the clogging up of arteries than high intakes of saturated fat and dietary cholesterol

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