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10.1016/j.snb.2025.137371 18 LongM.LiL.ZhangW

In aerobic microorganisms, O- demethylation is carried out by enzymes that can be divided into three groups: Rieske oxygenases (RO), cytochromes P450 (P450s), and tetrahydrofolate (THF)-dependent demethylases [26]