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Acid-alkaline Balance: Role in Chronic Disease and Detoxification

Nonetheless, when metabolic and stress thresholds are exceeded, this regulatory mechanism shifts from maintaining homeostasis toward pathways that trigger apoptosis, senescence, and cellular dysfunction

Inhibition of ODC1 with difluoromethyl ornithine (DFMO) reduced the production of toxic byproducts and improved memory performance in APP/PS1 mice, a widely used transgenic model of AD

Therefore, DNA damage in spermatozoa is primarily related to oxidative stress [45]

the main enzyme involved is therefore uridine diphosphate glucuronosyl transferase (UDPGT)