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And they know it

10.1016/j.jbc.2022.101768

IEEE Eng

Recently, it has been demonstrated that the RNA interference pathway is critical for the recruitment of methyltransferases to sites of heterochromatin formation

After all, this is how doctors have had to "practice medicine" for centuries - it's only recently that we have discovered the genetics data in detail, but science still doesn't yet have a broad knowledge about how to use it all (it's a pretty massive learning curve that the research world has been working to better understand)