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In vitro ATP binding assays were performed with recombinant GST-PDK1 WT and K163R proteins purified from E

The enzyme is a homodimer, composed of two subunits of 63 kDa each

In laboratory adipocyte cultures, the peptide has been observed to stimulate lipolysis the enzymatic breakdown of stored triglycerides into free fatty acids and glycerol while simultaneously inhibiting lipogenesis, the re-esterification of fatty acids back into storage triglyceride

Therefore, Billings LK, et al