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Conferring liver selectivity to a thyromimetic using a novel nanoparticle increases therapeutic efficacy in a diet-induced obesity animal model

This medicine is commonly used under medical supervision for managing nausea and vomiting during pregnancy , morning sickness , and for supporting Vitamin B6 and folic acid supplementation during pregnancy

In: Bergmeyer HU (ed) Methods of enzymatic analysis, 3rd edn

Hofstetter W, Smithers M, Rizk N, Lerut T, Nason K, Luketich J, Orringer M, Chang A, Low D, Darling G, Altorki N, Ferri L, DeMeester S, DeMeester T, Vallboehmer F, Crabtree T, Little A, Van Lanschot JJ, Rice T, Blacksonte E, Miller D, Yang S, Salo J, Peters J, Blackmon S, Krasna M, D'Amico T, Varghese T, Ajani J, Correa A, Swisher S

The acquired knowledge is expected to be instrumental for the development of novel therapeutic classes of medications to be tested on top of standard of care with optimized renin-angiotensin-aldosterone blockade and sodium-glucose cotransporter-2 inhibition, in order to further improve the clinical outcomes of patients with proteinuric chronic kidney diseases