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The KD was also shown to increase anti-inflammatory responses in glaucomatous mice, evidenced by increased expression of Arginase 1, a marker of neuroprotective anti-inflammatory microglia, as well as increased expression of the anti-inflammatory cytokine IL-4 in retinas and optic nerves (40)

However, timing mattersNAC is best absorbed on an empty stomach, away from protein-rich meals that might compete for absorption

and Pharmacol

Its three-amino-acid form belies a mechanistically sophisticated action direct intracellular NF-B inhibition delivered via a gut-specific transporter that self-upregulates in inflamed tissue

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