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Endoglin, a TGF- binding protein of endothelial cells, is the gene for hereditary haemorrhagic telangiectasia type 1

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Glycerol 3-phosphate is then oxidized to DHAP in a reaction catalyzed by glycerol 3-phosphate dehydrogenase (EC 1.1.1.8), during which NAD + is reduced to NADH