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MAPKs and the Immune System Many pathogens target host intracellular signaling pathways, including MAPK pathways, to inhibit immune responses (Roy and Mocarski, 2007

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Genes upregulated by GSTO1 siRNA showed significant enrichment of amino-acid deprivation response-related gene sets 29

Such a limitation can be overcome, for example, by including a copy of the gene sequence for a xenobiotic ortholog of the native protein in with the gene sequence of the novel variant gene in one or more cycles of DNA shuffling