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Acknowledgements We thank Elisabeth Rushing (Institute of Neuropathology, University Hospital Zurich) for support with the analysis of histological sections and Friedhelm Bladt and Frank Jhrling (Merck, Darmstadt, Germany) for providing EMD1214063 and for helpful discussions

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Anna Helova Deputy Director Sparkman Center for Global Health University of Alabama at Birmingham Yodi Mahendradhata Professor & Dean Universitas Gadjah Mada Malabika Sarker Chair & Professor of Practice Brown University David Peters Professor & Dean York University Support our young researchers and visit their interesting posters in the 'Galleria' (Lower Level)