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Science 353, 179184, doi: 10.1126/science.aaf6756 (2016)

The research only status requires strict limitation to in-vitro testing and approved animal research protocols under qualified supervision

In compliance with the recommendations for public health, anyone with a cough, fever, loss of taste/or smell, flu-like symptoms

For long-term studies, this can sometimes present practical challenges, especially if high frequency of administration is required

Two preclinical studies showed benefits of ascorbate in a familial ALS mouse model, and there are two case reports indicated that ascorbate was associated with improvement of the disease