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Future Perspective VEGF is critical for embryonic angiogenesis, although its activity in adults is mostly limited to the angiogenic processes of the female reproductive cycle and wound healing

Too, the study of the therapeutic effects of combining RT with FOLFIRI regimen, comprising leucovorin calcium (calcium folinate), 5-fluorouracil, and irinotecan, plus bevacizumab in metastatic CRC also noted objective response in 10/10 patients (3 partial response and 7 complete response) [184]