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doi: 10.1038/nature12721

Two reviewers independently assessed study eligibility, extracted data, and assessed studies for bias

This was due to the repulsive forces between the negative charges on the AuNP surfaces and bacterial cells, thus preventing the interaction between AuNPs and the bacteria [21]

In awake rats, analgesic amounts of a dermorphin analog stimulated respiration through central mu1 receptors, while higher, cataleptic amounts depressed breathing and blunted the response to carbon dioxide