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Specifically, eligible studies included participants (P) with a confirmed diagnosis of vitamin B12 deficiency, interventions (I) involving oral or sublingual vitamin B12 administration, comparators (C) using intramuscular supplementation, and outcomes (O) reporting changes in serum vitamin B12 or homocysteine levels

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Signs of infection include pain, redness, swelling and hotness at the injection site

Patient education: Tinnitus (ringing in the ears) (Beyond the Basics)