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Due to the complexity, and size limitations associated with the cobalamins, the primary method for calculating ground state properties is density functional theory (DFT), while time-dependent DFT (TD-DFT) is used for electronically excited states

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J Anal At Spectrom 16(4):390397 Suzuki KT, Mandal BK, Katagiri A, Sakuma Y, Kawakami A, Ogra Y, Yamaguchi K, Sei Y, Yamanaka K, Anzai K, Ohmichi M, Takayama H, Aimi N (2004) Dimethylthioarsenicals as arsenic metabolites and their chemical preparations

Furthermore, SGLT2 inhibitors can enhance HIF-2 activity via a mechanism that relies on SIRT1 (276)

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